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Title   간 절제술을 시행한 간세포암 환자의 연령군별 임상적 특성 및 치료성적 비교 ( Age-related Clinical Characteristics and Outcome of Hepatic REsection Therapyin Hepatocellular Carcinoma Patients )
Publicationinfo   1997 Jan; 029(05): 825-833.
Key_word   Hepatocellular carcinoma, Age group, Clinical characteristics, Treatment results
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Abstract   Purpose: A retrospective clinical study of 213 patients who underwent curative resection due to hepatocellular carcinoma was performed in order to compare the mortality and survival rates of elderly patients with those of younger patients following the resection. Materials and Methods: All subjects underwent curative resection at Shinchon & Yong- dong Severance Hospital between January 1985 to December 1994. The subjects were classified into three age groups: Group I(n=26) under 40, Group II(n=142) between 41 and 60, and Group III(n=45) over 60. Variables considered include sex, family history, accompanied diseases, Hbs Ag, a-PF, Child classification, operative method, resection margin, number of mass, size of mass and gross-appearance were evaluated by X-test(p=0.05). The one, three and five year survival rates were analysed in each group by the Kaplan- Meyer method and survival curves were compared by the log-rank test. A probability of <0.05 was accepted as significant. Results: The results showed that elderly patients have no significant differences from the younger patients in any of the variables considered including postoperative morbidity, survival rate and disease-free survival rate, except for the family history and positive Hbs Ag in which the elderly patients showed significantly lower values. Conclusion: These results suggest that hepatocellular carcinoma in the aged can be treated in identical manner as in younger patients.
저 자   조옥구(Ok Ku Cho),윤동섭(Dong Seob Yoon),권성원(Sung Won Kwon),지훈상(Hoon Sang JI),김병로(Byung Ro Kim)